Understand and reduce the health risks
Assessing the level of toxicological concern associated with NGPs and their ingredients, device materials, emissions and products as a whole.
Understanding possible biological responses to speciﬁc endpoints of products as a whole or on a single substance basis.
Storing chemical information and toxicological data associated with substances related to products.
Providing expert toxicological advice on new products, or modiﬁcations to an existing product, on their appropriateness for the protection of public health.
Becoming a long-term strategic toxicological partner to clients providing consultancy services across the Product Stewardship lifecycle.
Toxicological studies involve a tiered approach of data gathering and risk assessment depending upon the product. The ultimate objective is to develop an informed and scientiﬁcally justiﬁed assessment of the risk to health presented by a product. This involves considering the nature of any hazard presented by an ingredient, exposure levels and the dose response, which collectively enable risk characterization.
Toxicology services offered by Broughton are represented by two core areas:
Desk based toxicology services.
Evaluating the potential health risks associated with exposure to contaminants or other residues in a product.
Gathering regulatory in-vitro toxicity data through designed experimental toxicology studies to determine the effect of a chemical substance or the formulation is an important part of a regulatory dossier.
Broughton in-vitro testing services include:
Our team of experienced toxicologists will design and manage your studies to comply with regulations including US PMTA and Medicinal Products. Broughton is a Good Laboratory Practice certiﬁed Contract Research Organization (CRO) facility.
Toxicological studies will often include a tailored mix of different types of studies according to regulatory and/or product development requirements.
Broughton has developed a custom database, named ToxHQ, designed to store critical safety information on products and their ingredients.
Discover our videos, brochures, infographics and much more.
Learn more about the process for toxicology risk assessments for ENDS products.
Understand what’s involved in a PMTA and how the recommendations relate to your ENDS business.
From basic questions to complex compliance inquiries, we're here to help! Contact us today.